I can tell this is going to be good, this actually blows a lot of other games like it that I've played straight outta the water. The only thing it lacks is content, but the bones for something truly amazing are already there (and let's be real, making animations & drawings that good is not gonna be quick).
The intro made me expect the game would be way darker than it actually is. That illusion got dispelled pretty quick of course, and honestly the game is great the way it is. It's just the right mix of goofy and serious.
...also I hope Suzume gets a couple more scenes by the final version. I know she's not exactly a major character, but there's something nice about confident girls who know exactly what they want.
Tiny nitpicks related to controls ahead:
Arrow keys work for movement but not for fast-fall (though it seems like arrow-keys + z+x+c for attacks & shooting and such would be a good control scheme for this game if there was a way to fire in the direction your movement controls are pointing sort of like in Contra).
There's no built-in deadzone on shooting via right stick on controller, so unless you're using Steam Input or something even a TINY analog input will make you continuously shoot in the direction you're aiming, wasting ammo. You might want to check the vector's magnitude before you normalize it, and only fire if it's above 0.15 or something like that, maybe higher depending on how it feels.
There's a separate input on keyboard for interacting with things, but on controller, any up input is considered a command to interact. Since there's no ladders in the game right now this is good actually, and might be worth bringing to keyboard if you don't plan to add any, to keep the control scheme compact.