Currency disparity is a valid concern. I don't think it's an option on itchio indeed, we are going to consider regional pricing for steam, and I think it was great and fair for a very long time. Unfortunately people abusing the system using VPN has made things very difficult for dev to do that now... and even when there is adjustment they are minor (like the price might be lower but not super low).
It's something that need careful consideration and thinking. Like we will probably do some level of regional pricing following the steam guideline (which as I said are not as generous than before). But maybe I could do other alternative... Like it would be cool to do a partnership with a Brazilian outlet or streamer and have them distributing very cheap keys for ex, I really don't mind "devaluating" my work if I know it goes toward the right person? But then, I also don't know how much English speaking VN fan there is in Brazil either and since I don't speak Portuguese it's hard to reach for the right people...
Anyway, I am rambling, but I heard your concern! <3