Since there is no way to advertise your game on itch, there is no best way.
Make your page and title search and findable by regular internet search.
Make it visible for people actually looking for your content within itch by having relevant tags.
But your main promotion and advertisement should happen external. The things happening on itch are mostly passive and random. But you can look where some of the people looking at your project came from and maybe improve on that information.
Also, promotion within itch is kinda discouraged. There are very few places where you can do that. But even an announcement thread ... well ... just look at the view counter on those.
If your project is in development you can post a monthly devlog or something.