Writing this to summarize my observations while playing on the newest game patch.
One major chance I noticed are the increased odds for buildings/structures and Life Fruit spawns when I compare it to the previous version where I could play for hours but get no new Life Fruits to spawn and just a single merchant per 5 new worlds. Which is an welcomed addition.
So going to start with the new interaction system, it works well for its intented purpose but it also allows you to issue a request to a male character to be on the receiving end, which in on itself is surely intended, but I can do so while playing a female character so it just looks little silly. From the available poses to me currently it only seems to trigger with the 'Missionary' one. (Attaching a video to showcase it.)
Would obviously make sense with something like the toy Sophia owns, but unless I am playing on too early level to obtain such divine artifact then excuse my gap in knowledge.
After some playtime, it seems to work on both, male and female NPCs, and also with the 'Doggystyle' pose.
When NPCs react to a naked character with their lower exposed, they say the following line - Whoa.. YOU'RE [insert genital based on gender] is out.. That is a clear mistake in typing as YOU'RE shall be replaced with YOUR.
Lastly, when I attack an enemy in quick successions - only when they are stunned and laying on the ground, sometimes they just get flung high into the air and land down shortly after.
Sometimes all wandering NPCs struggle with slopes, not properly path finding around and getting stuck on the vertical part of each slope, jumping in one spot, unless you get their attention. (Attaching a video to showcase it.)
For ledges: Skeletons refuse to jump down on occasions after being attacked. Neutral/friendly characters won't follow you sometimes, unless pushed down. Which I am certain was present even before this patch now when I think about it.
That might be everything I have came across and from my thought about the newly released patch.
Thank you for reading all that.