I really appreciate the premise of this game - having also watched as two of my grandparents suffered with Alzheimer's, it really struck a chord. Let's hope they eventually find some sort of cure for such an awful disease...
The music itself is great, too - it definitely sounds authentic, and all of the oddness you included really works to give the songs a sense of confusion. Being compatible with real Mega Drive hardware is a bonus!
Excellent job overall!