Decently expansive game you've made here. Didn't get to the end of it but I am interested to see how the end game looks for this. At first I felt it was a bit confusing when it came to learning the mechanics, but messing around a bit allowed me to figure it out.
The UI was very good, however I felt the periodic table page looked a bit overwhelming, although simple in terms of gameplay. The power bill mechanic is a very cool way to link the Shadows prompt to this game.
Overall very well produced game that I would like to see expanded on further, rather than just being a more sandbox/linear experience. Awesome job!