Cool game, interesting crafting system.
It's a good idea to have multiple cauldrons throughout the level to avoid backtracking, but due to proc-gen the first 3 rooms I visited were all cauldron rooms with no enemy so that felt weird xD.
Maybe instead you could have a cauldron appear after clearing out a room of enemies?
Also I think I had a bunch of debuff at the top of the screen and was taking damage over time but didn't understand why.
But I love Isaac-likes and being able to craft new weapons very regularly was very fun.