That depends on if I've had to update the save/load script in new updates - I need to update the script any time there are new variables to be saved, such as from new powerups, entities, objects, interactables, and so on. I'll usually note in the changelog if I've had to update the save/load script. If you want to quickly regain lost progress, you can use the debugger to give yourself DNA points as well as do a couple other things - check the readme file for detailed info