The art and visual style is great! The 2048 gameplay was great and the twist definitely made it more unique. I think it would be cool if the slimes also changed color as it would make it easier to see what state each slime is in along with making the game more visually interesting. The isometric perspective with directional keys took a bit to get used too, maybe a little icon or arrow on each side so it's easier to tell what key needs to be pressed would fix that. The UI could be a bit cleaner to match the game visuals, but it's good enough. Great idea and a good execution, well done!