Hi Jumma!
Sorry, I am unsure what you are actually asking. If you mean to ask what programs i use to make my assets, I use PaintTool Sai, Gimp, and a few others. If you're asking if I'm making these assets to be used with a specific software, the answer would be no. I use them in Ren'Py, but they can be used with other programs too.
I hope that answered your question =]