First of all, nice choices on the sprites/artwork and music! It feels very cohesive with one and another.
The concept of trading your life points for upgrades is interesting! I can see it being able to be developed upon in many different ways.
Quite well done for your first game! Pretty much all of the systems work as intended, and with the exception of the room boundaries, I don't remember encountering any weird glitches.
There's quite a bit of things you can learn as you keep game deving, like art, music, and etc. It's a long but fun road. I hope to see you next jam. Keep making stuff!