I'll try to tackle these one by one.
1. If you mean that there are no more rituals unlocking, that's how it's supposed to be for now. The threesome is the last ritual currently.
2. That part is not in the game yet, sorry. It's just some setup for the future.
3. Hmm, I think I might've fucked up something with her quest. I don't think you're missing out on anything with her right now though, so feel free to ignore Serena for now.