You'll have to be more specific about the problem you're having. If it's just setup, here's a step-by-step guide:
1. Extract the 2 folders in the zip to your project's root folder.
2. Open the Plugin Manager and double click an empty line. Press the Name box and select "r88_Lockpick".
3. Make sure you've set the "Item" parameter in the Plugin Settings (this is the item that represents the pick), or you'll get an error. Click "OK".
4. Make an event and open the Event Commands window. Go to the last page and click "Plugin Commands". Select "r88_Lockpick" under Plugin Name and press OK.
Now, whenever you trigger the event, the Lockpick scene should open. The minigame will only start if the player has at least 1 lockpick item, so make sure that you give them one.