You need to focus on improving unarmed combat skill to at least 50% because you can only use this skill at the fight club. The easiest way is to fight drug addict at the abandoned flat and fight them with only punch or kick. Don't use weapon such as pipe etc. You can also talk to Prenny at the abandoned flat and ask to buy medical supplies. Sometimes she has crimson tea for sale. You can drink crimson tea to add 20% to combat skill temporarily to make it easier to hit enemy.