This was really interesting! I loved the 4th puzzle in particular, where you needed to figure out what each item did to the patterns. The story is interesting, you say it's a fictional condition, but it looks like dementia to me.
There's a really nice, cozy vibe with the art and music, but it doesn't really match with the tragedy the main character is going through.
The smudges on the pages caused problems on the puzzles, I couldn't see that there was a water drop on the grid in one spot so I placed one there and thought I was missing one.
Overall, I liked it, particularly the way the minigames matched the story.