My main point is, renpy is optimised for visual novels. A point & click game is not a visual novel. If you use an engine optimised for one thing to do another thing, this might show somehow, or make certain tasks extra difficult.
But this goes in the other direction as well. Visual novels made in other engines often lack a lot of the quality of life basic features one expects from a visual novel. Like rollback - scrolling back to previous text. Or configurable text speed. I curse every time I play one of those and the dev did not put any thought into making text speed configurable.
For a point & click a thing like rollback is usually not needed at all. You do not even have an interface with those text boxes. Many point & click also have an avatar running around on screen. I do not think I ever saw a renpy game re-creating that feature. If you want to see renpy games that "break" with visual novel mechanics, see some sandbox and management games. Maybe adventure too. And of course the point & click ones that are not tagged visual novel.