I don't use zoom plugins, I just make everything bigger by doubling it's size in (200%) in Aseprite. Sometimes, that includes tilesets (to scale them with the bigger sprites). My sight is a bit poor, so that's why I prefer games with bigger sprites. My last game used smaller sprites and playtesting it was painful to my eyes, so I'll always try to use bigger sprites (it also allows players to appreciate sprites in more detail, for example, shading, dithering, animations, etc)