I would say IMHO defense definitely needs to be nerfed on both sides. In my experiences a lot of battles (especially with higher level enemies) seem to end up with both sides dealing chip damage making it more of a war of attrition than anything else. Or in the case of lower level enemies they can barely do anything at all while I can one-shot them only being one or two levels ahead. DoT effects like poison and burn are the only thing that seem to deal reliable damage at present. Even super-effective skills and crit hits are often only landing for 1-2 dmg.
Also one more thing: An auto-submit skill for those of us who want to view the loss scenes without having to wait for enemies to wear us down would be nice. :P