Yes!
That's one of things I'm trying to improve on with the current reworking as well. At the moment, you can say Mc is friendly (and doesn't seem to be a reason not to continue) with Avis/Koko/Raiko, but much less so (depending on choices also) with Serena, Levy, Valentina and Eiko. It was a bit unclear from my own previous writing, but it should be showcased a bit better in rework.
So yes, MC will be friendly with all of the girls throughout the game and continue interacting with them, and some choices/pathing will be slightly shrunk to better portray it (like removing not tripping thief which locked you out of any meaningful Levy talk for 2 updates).