Hi!
That's weird. It must be something related to the system, as the game is made in Unreal and it has been working in all the people's computers. There's nothing fancy inside it.
Have you checked if your antivirus is messing around? your antivirus software could be causing the issue, Link 2
If you can't get the game to run you can find out about itchio refunds here, of course.
Let me know if you manage to run it to have that info for anyone later.
And thanks for buying it (and for using VR).
Regards.