I use Clickteam Fusion 2.5 for all my games. (Have been for six years)
I use C/C++ and Assembly when I try to make extensions for Fusion (See I said try, because I'm not all that good LOL XD)
Audacity and LMMS for Audio.
GIMP/Paint.net/Inkscape/Various pixel art makers for art.
And a stupid, drugged up brain for ideas and work stuff :/