Its been eluded to that dave can die or atleast will be able to (think grizz may have said somewhere that everyone can die including dave but mite be misremembering) and orlando tells you how he saw dave die and the vault does show things that have happened so lets hope its avoded.
If that would be the case, that's a relieve. Although, characters with plot armor are no fun. Then you have that strike of curiosity (at least I always do) to try and mess with the heavy stuff and see how the game handles it (that means even killing the protagonist and basically ruin the whole plot).