Hmm, I will look into it. I use HaxeFlixel so I don't know if I have such low-level access to Lime. Lots of thanks for the suggestion!
Add this to the style tag of your canvas:
image-rendering: -webkit-crisp-edges; image-rendering: -moz-crisp-edges; image-rendering: -o-crisp-edges; image-rendering: crisp-edges; image-rendering: -webkit-optimize-contrast; image-rendering: optimizeSpeed; image-rendering: pixelated;