I'm glad that my answers made sense! Cos I know I tend to ramble on a lot x3 haha.
SPOILERS
What you said about S**** screaming for MC before she was cloned is pretty spot on :D I mean, I didn't state it for certain in the game, so it's open to interpretation. It could be as you said, or it could just be that it's not technically S****, more like just part of the MC's subconscious memory fragments of him. Like her own memory telling her, you've forgotten something/someone important and you need to remember what it is. I don't mind it being either of those :3
As for why Kuro is called Kuro, you're pretty much right again with one of the things you said :3 Isaac was fine experimenting on OG MC and all her clones because she doesn't really mean anything much to him (kinda just a tool to use), whereas with S**** being his son, S**** means a lot more to Isaac, and he would prefer to sorta disassociate the Kuro's from his son.
That's the story reason anyhow.
Then there's the totally separate reason of just thinking of the general theme of black & white, light & darkness sorta thing. The Kuro's are all like twisted shadow versions of S****, but I couldn't just call the characters Black and White, cos that would sound a bit odd. So I decided to call them that in Japanese instead... it's terribly nerdy, I know >.< haha.
Yeah, poor S**** ended up becoming pretty twisted over time having to watch all of that going on, the poor guy :(
SR and Kuro are like my baby, haha, so it means so much whenever anyone says they really enjoyed playing it :3 I have suffered with anxiety and depression for most of my life, which has resulted in me having pretty crappy self-confidence, which then causes me to think negatively about anything I do. For example, there were many times (and there still are now) that my brain says what I'm doing sucks or isn't good enough >.< So when I hear positive comments, it really helps me to fight back against that negative part of me and help me believe in myself a little more! So thank you :3
I first heard the word Solipsism when I was playing Mass Effect 2. Thane mentioned it in a line and I just thought, wtf is that? I went to look it up immediately, ended up spending ages reading about it cos it was so fascinating, haha. I'll be honest, even now, I still find the concept a little difficult to wrap my head around >.< I wanted to be able to include it somehow though, even if I don't fully understand it!
If you take the true end as being 'reality', then I guess it would probably be a happy ending for everyone, including the clones :3 It's very open to interpretation what happened to them all, but I don't think that OG MC would have let anything bad happen to them. I like to think that they just let them freely live their own lives :D