Large textures will most likely be the case.
I wouldn't go over 1020x1020 textures unless it's something that really needs detail.
Also make sure that objects that don't move are set to static and that materials that are used a lot are gpu instanced.
I'm speaking out of a Unity perspective here, not sure about UE.
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Thanks. Its been a pleasure talking with you. Please feel free to message me on discord any time with any game related topic you find interesting. Your website says you are making a game? Edit, I also see a drive thru rpg link. I was considering making a pen and paper rpg for free rpg day to promote my game. Big tabletop rpg fan, mostly osr these days