I got the hang of the melee system fairly quickly. But despite playing a lot of games the timing seems awfully tight. If I have, at times, difficulty reacting in time, I wonder about other people or who due to disability have problems to react quickly. It will be a very frustrating experience for them, whereas the rest of the game might very much delight them.
What confuses me at the moment is ranged combat against me. I see a red/orange/green bar with a slider and I am still unsure if I am supposed to press something in return or if that's the enemy using the ranged combat bar.