I do not have a Mac or Linux system and do not know how to set up Wine, but awhile back one of our Buccaneer's Reef members did contact me about it and after some testing, he was able to get Maelstrom working on a Mac with Wine wrappers, but only a version with the older VC runtimes, from Visual Studio 2012 (the newer VS 2017-2019 runtime versions did not work properly and that might be due to Wine will always be slightly behind, due to them needing to reverse engineer the Windows runtime features; maybe they have caught up by now for 2017-2019? I don't know). So what I have done is maintain a version of Maelstrom, with all the same code (fixes/modifications), but compiled under the older Visual Studio 2012 and whenever I update, I also recompile a version for him and send it to him. What I can do, is add a "Wine compatible" version that I will put in a subfolder of the Maelstrom download, which I will do in the next update I submit to Itch this weekend.
I only have his word that he was able to run that version in Wine and he did mention that he had to change some things with Winetricks, but again, I don't know anything about the setup process or whether it actually runs as he claims.