So, you have some sprite masking as well here, when she's looking through the window... In curious if there is a way to do it straight in GB Studio?
EDIT - Wrong page, sorry! Will post this question in the right place.
I'm not quite sure what you mean...
If you mean the 3 different scenes in the (admittedly square) thought bubbles, I ended up just making 3 copies of the background and changing the content inside the thought bubble for each. They're 3 different scenes under the hood.
If it's something else, I'll do my best to answer after a clarification!