The graphical quality and audio design of this game are phenomenal, though I think the level design could use some work as finding the way forward can be difficult and obscure and with the doctor hounding you it can be hard to really explore. I only really managed to figure things out when I got the doctor stuck.
In case anyone else got stuck as I did, here's a simple walkthrough:
(SPOILERS!!!!)
To progress in the first area; you need to find a filled syringe of anesthesia and pick it up, then click the doctor to put him out. This syringe can be found in a closet off to the side of the second room of empty syringes you come across (not the one in the prison area. There are two places like this.) If you're having trouble finding it I found you can get the doctor stuck which will give you unlimited time to search. Just run out of the prison and talk to him in the doorway like you normally do. then, run all the way back to where you started the level and close doors behind you as you run. He'll follow you for a short while then give up and return to the hallway. When he does, move to the final room in the prison area but don't go out the doorway you meet the doctor in. Stay in that room and listen. You'll hear the doctor go and check his office, come back, wander around in the hallway for a bit, then check the closet across from the prison exit and get stuck walking in place. Once you hear him walking endlessly without actually moving you're safe to go out and explore. Once you hit the doctor with the anesthesia you need to wander around until you find the stairs and go down them and out the door down there.
For the second (and currently last) area; as you explore you'll encounter a hospital patient crawling on the ground at incredible speed who changes his mind after first asking you to unclog the toilet and instead just wants a glass of water. You can find it nearby the bathroom in one of the other patient's rooms on a nightstand. The way to progress is with a crowbar. It can be found in another random closet near the beginning of this area just off to the side of the large room with all the curtains and beds; to the right of where you entered the room the first time. Once you have the crowbar you'll need to take it to the hallway with the bathroom. When you enter this hallway the nurse will be upset to see you carrying the crowbar so you'll need to juke her somehow and get past her to the double doors at the end of that hallway and use the crowbar on the boarded-up doors to the right. Once you reach this point you have finished the game.
Hope this was helpful.