Hey, thank you for your feedback! I am glad the accessibility settings work for you (you can also press 'v' to turn on self-voicing if you want a computer to read things to you).
I can see how the farming part would be difficult for you. If you'd like to continue playing, there's not really a way to lose the game by having a bad farm (but it's not very satisfying!). There is an Auto farming feature that turns on after you've beaten the game once... would it help if I added an option to turn it on from the preference screen?