A very promising start to a great game (in general), The story/lore is something that actually intrigues me, and I thank you for coming up with something unique for a background universe that isn't just the standard story models I see in the other H-Games on Itch.
I was slightly disappointed that you could change more "Integral" parts of Sam (Although my MC's name is Ashe), like height and cup-size for example, However some quick answers I came up with to explain why this can't be done are as follows; The law of the conservation of matter, Genome Destabilization, or it's going to be an absolute nightmare to re-draw every single clothing option for every possible body type.
On the browser version, the images really do not like to load often, and scrolling up once makes the game unplayable for about a minute straight while it recaps the dialogue, but that's the extent of the issue I found on what you literally call an unstable build.
This game and the universe it is held in seem to have a lot of potential, and I'd love to see the concept expanded upon furthermore, for example you could have perhaps another game where the crew of the ISS have to evacuate the station (Because barely anyone on Earth bothered with NASA affairs during and after the Pandemic, and so they were absolutely bone-dry on resources), and the crew has to come to terms with them being the last Middle Aged humans post-pandemic, and having to figure their way around a world that completely forgot of their existence. You can see what I mean by how far the concept can go, and that shows the brilliance of it.
To end this Mini-Review, Keep the bonfire going, soon enough salvation will find you.