I'm using Windows 10 64x Bit. And yeah im using the right .exe to open it. No i haven't used Renpy Before. And i don't know what Zsynic is.
Edit: Tried Clicking the .EXE In the folder and it just dosen't open. It adds in a games list in my Gaming application without it running.
Edit2: Worked! i had to Uninstall the whole Itch.io and Install it again. Sorry to waste your time for a simple solution. Seriously. So Sorry to waste your time.