WinUAE will work, yes. From AmigaOS you will need to create a blank bootable disk, create directories "s" and "libs" on it, copy the game files to it, copy diskfont.library and mathtrans.library from your AmigaOS LIBS: directory to "libs", and finally create a "startup-sequence" file in "s" to run the SantaRocks executable. It should autoboot then.