I really like the topdown perspective and the Binding of Isaac room style.
I just thought that the shooting mechanic could be improved a little bit, not the sound effects, "pew pew" were a awesome. It's strange for me using the mouse only to shoot and not to guide the player facing direction. It makes hitting enemies harder than I think it should be because you have to carefully align yourself instead of using the mouse to aim which is more intuitive. I also think that the big spider hitbox was smaller than I would expect it to be.
But overall a very nice game.