I'm glad to see someone went with the enhance/zoom interpretation of the theme. I was drawn to that but couldn't figure out something - going deeper fighting bacteria is a cool idea! Difficulty is rather swingy and punishing with only one hit kills - I had runs where the second zoom seemed to take forever, and one where the whole screen was covered in enemies and i was able to basically instantly move onto the third. I think it's on the fourth one where the green guys start showing up? I think there's something interesting in the idea of a an enemy like them, where shooting them is something you're actively trying not to do with a ship that constantly shoots. Their unkillable offspring aren't visually distinct enough to sell that they can't be hit - unless they were supposed to be killable, in which case they definitely weren't working right. I didn't last long enough on the last level to see if anything had changed there.
Audio-wise the music got real repetitive real fast, with just two measures repeating the whole time? I think there was a missed opportunity for something cool by syncing the constantly-firing gun with the music, using its sound as part of the track. The enemy death sound's a little noisy/scratchy for me.
Art was fine, though the shape of the ship makes it kinda hard to judge exactly where your hitbox is - not that I was eager to test that out, with the one hit kills.
Anyway, this is a really solid entry overall and I love how you used the theme!