I decided I'd record a run, and eventually got to this point:
Yes, that is 100 regeneration under my character (thank you, My First Wand + Wizard Cap, for being utter nonsense). The entire run was a cakewalk up until I got into this fight, where I died on turn 3 from Fire Geckos being jerks. That said, if I had seen a single damage-dealing wand, I could've wiped them off the field with minimal effort — generating 5 mana a turn is really, really nice, especially when you have a Whetstone backing it up.
Add me to the chorus of people who think there needs to be a better way of dealing with poison — the rag in the top-left of my inventory is the only kind of anti-poison item I ran into on my run (other than some Cleansing Potions, but those hardly count).
Maybe the Cleansing Wands (which I ran into, like, 12 of) could clear your debuffs instead of clearing enemy buffs? Or maybe poison could "eat" regeneration before it hit your health? I dunno, I just think that it's a little odd that there are only a handful of items that can deal with poison effectively, especially given how much of it gets thrown around by some of the enemies in the endless mode.