I love that you got creative here with the patters. All bosses felt different to deal with. Good job!
As others already mentioned, people with sensitive eyes could not enjoy this game to the fullest currently. I'd advise muted colors, but this is again depending on the overall style.
For Toxic Bok's homing missiles I'd suggest adding a blinking animation or something similar to indicate that they'll blow up. Was not clear for me from the start.
I hope you keep on making games if you enjoyed this jam.