Tried a couple of runs, made it as far as the Graveyard biome as the hiker/backpacker class
Game is quite fun, didn't have any bugs or issues that I've noticed. During that run, my hiker got a berserker mutation, and it was a lot of fun watching him walk to up random rats and beat them to death.
I haven't played many of these games but I can't think of any that handle the camera like yours did. I thought it was interesting and innovating. Throughout my runs I stuck with the 'standard' 2d view.
Only suggestion would be making it easier to place things in your backpack, where dragging an item over it would swap items instead of placing the item in the backpack. Instead I needed to have the item ready to place, then open the backpack and place the item in one of those slots - I think that's one step too many.
Final score: I will buy this game on steam once you release it / 10