The asesprite beta crashes immediately for me T_T I still have to troubleshoot. Maybe it's possible to fix?
I'm only able to use Asesprite by using the existing release.
Viewing post in Isometric Box Generator for Aseprite comments
I've heard people had some crash issues on Windows 10 because of the wrong beta branch. Make sure you have selected branch called beta - Beta version - Preview features in Steam.
https://twitter.com/AlphieStudios/status/1063348105599344641