(See picture) 
Very sad when this happens D: Basically I get a lot of minus points. The total randomness of the game makes it extremely easy to get unlucky, and that drags the game out by a LOT. The most frustrating would be gathering the needed color circles to mix them into the correct color. It took me so long for those.
One of the ways to make the game less tedious and make the player feel less bad having to get rid of 6 value dice and get minus points is to increase the spawn rates of the lower value dice. Also, do something about the coloring as well - make it less tedious for the player to wait for too long for the RNGesus to appear and say "ok it's been 3 minutes, here is your red circle. Now wait for another 3 for a yellow circle so you can make the orange dice xd".
Or, maybe remove the minus points system entirely, since it only drags the game out.
The art is good, the audio is also decent, however.
Also I ranted for quite a lot because I actually got to 20k points, and it was a bit frustrating :v
Totally personal opinion, hopefully I gave you some good Karen-like insights (yes I am aware that this sounds like a Karen throwing a tantrum).
P/S: I couldn't give live commentary due to not being able to stream, sorry