Cool concept! I really liked the pixel-art and the variety of power-up!
However I faced one main issue: there are too many dices! :p Since letting one fall makes you take damage, I was constantly spamming the S key, and could never really use any ability or even just focusing on what's on the screen. Especially once enemies come from behind, it's hard to really examine the situation. My brain was also too overloaded to switch properly between dices. So I couldn't get very far, most of the times I let too many dices fall, or I focused too much on them and got killed. At least I think I killed the octopus once!
It was still fun to play. I like the core mechanic, the power-ups were fun to discover, and if it wasn't for the dices the patterns seemed pretty balanced. It might need just a small adjustment to make the idea work just fine. Good job overall!