https://forums.rpgmakerweb.com/index.php?threads/easy-mac-porting.41524/
I suggest using wineskin instead since it for a mac but for linux WINE FOR THE WIN
Also question since the game is free would you provide the source code for the game so other people can try porting it to Mac and Linux?
Viewing post in Lonely Wolf Treat: The Complete Series comments
The problem is that RPG Maker (VX Ace in this case) is proprietary, and Nami doesn't control that; as far as code is concerned, the game's authors just write scripts and use libraries published by others (from my understanding of RPG Maker game development), and that doesn't help porting unless you are prepared to redevelop the engine's functionality from scratch. There are free/open source reimplementations of RPG Maker runtimes that have done that work (such that you can port existing games to the new engine), but the newest one I'm aware of only covers RMXP.
(Incidentally, RPG Maker MV has a whole different architecure (from what I can tell from the outside) and actually exports a HTML5/JavaScript application, which can in theory work wherever; but I gather it's more difficult for some creators used to working with earlier RPG Maker editions, so...)
(Also, if you wanted to take a peek at the game's Ruby scripts and stuff anyway just out of curiosity, you can get those from the game package itself... but that would be in violation of software copyright, especially if you subsequently modified and/or distributed them...... and that would be very rude regardless......... pls be nice............ u saw nothing)