Uniqueness and fun really wins it for me- It has a really nice item system and fun recipes. It was fun figuring out how to handle the supply chains in a way that would minimise waiting. But as with all jam games, I'd like some more QoL- A more clear indicator that you're dragging a machine would be nice, and an easier way to see recipes would be too. This game has the reverse-alterhistorian problem- You can only zoom but not move, which makes it a bit clunky. It was slow to see the recipes via holding down left click too.
Balance could do with some work- It was quite tedious in a few of the places especially after discovering the two new locations, which was not helped by the obtuse controls and claustrophobic interface (Which I wouldn't blame too much, given my game has the same issues)
Theme wasn't really used that much until the end, where you start brewing essences.
All in all this game is one of the better ones in a jam where I felt like the entries were already pretty good already. I was actually excited to see what expansions would give and what question marks would do. Nice job.