PDF? Do you mean PSD? PDF is an export format, it's not designed to be modified (which is why it's such a pain to modify them). PSD is the default photoshop filetype. Enormous filesize, very easy to modify (with PhotoShop or GIMP).
"I want without quality loss, and that is also why I am not using vectors or anti aliasing."
... That requires a more complicated response. Do you have Discord?