Log in inventory shift to center area, where most loot ends up in it self kinda of not greate short all loot from one spot, As far log in move map weapons - potions food to 4 corners log off - log back in weapons potions all shift to middle jumbled. then have to reshort all stuff. I will see with update if issue fixed.
Are you logging in from the same computer every time? The game saves a local file that stores the position of all the items; if you log in from a different computer it won't be able to load it and will default everything to the middle.
Does it happen every time or just some times? If it's a problem every time you log in, then you might check that you can write to the ProgramData directory, for howlbreath it's at: C:\ProgramData\howlbreath\. When the inventory configuration is working correctly, you should have a ".bagcfg" file for each character in that location. If it doesn't occur every time, then it's likely a bug in the client -- if this is the case, any details on when you do/don't see it would help us reproduce so we can fix it.
We didn't change anything in regard to the inventory locations, so I would expect the issue remains.