What version and platform are you playing on, and does the game not even start or does it crash into playing the game?
version 0.10.10, platform windows and it crashes soon after hitting start game
Do you have an errors or traceback file in the game folder you can post for me to help you diagnosis this? If not, try to delete the game folder and reinstall it (don't worry; saves are stored in your appdata folder and won't be deleted)
Following up on this. Did 0.11.0 fix your issue?