I ran this with friends over the weekend, and while scheduling made it so we were down to four people total, we made it work! It was a little bit chaotic because of it, but very much still doable! Everyone had a fantastic time putting on different character voices, and some character accents changed halfway throughout the game or, in my case, halfway through a monologue.
We had two people sitting in who wanted to see what it was about before jumping in, and they're both going to join for episode 2 which we'll be doing at month's end! Had a great time with this game, cannot stress enough how nice it is to just give people scripts and have that be the extent of what needs doing for setup!
We play online through a discord call and there's no problem with that whatsoever. The characters all have distinct personalities and, in our group, people spent a few minutes deciding which aspect of their character's personality they wanted to play up the most. We all had fun talking through the 'whodunnit' at the end, and the conclusion was delightfully fun. The Wytecliffs are a fascinating family and if you've got 90-120 minutes and a desire to run through a fun story, I'd suggest giving The Ghost of Northwood House a go!