So hopefully the issue solved itself for those down below.
(Not being able to start the game)
If not then I'm not too sure but for me I've been able to start the game
Playing on Windows 10 and I'm sure Windows 11 can start it as well
Running this game through the Itch.Io Sandbox Launcher - Its an app for convenience of use for those who want to buy the game.
Here is the link https://itch.io/app
Once downloaded head into Preferences and check Sandbox Mode
Hopefully this solves some issue although it might be a software issue on your end.