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(+1)

Oh that's definitely a DI thing. If that triple hit is easily readable you can weasel out of it most of the time on 1st hit at correct DI angle. 

I recommend checking if they can escape a 3 hit combo before locking in. 

(+1)

ever talked about cowboyS 1000 Special?

Yeah, that one too, it makes many moves with slow startup too risky to actually use in combos while it's active & leads to the opponent recovering a lot more quickly after Izuna Drop

But so far, it seems like the answer to that is always "yes"!
Usually, even the slightest DI in any direction at all throws the 3-hit combo off.