Pretty dope overall, nice work! Huge variety of enemies, lots of content for a jam game!
Took me a bit longer than I'd like to admit to figure out I needed to lock onto an enemy to punch them at the start haha, maybe a basic "Press F to Lock On" prompt for the first fight would really help here. I didn't really understand the powered up fist mechanic too well either (how to unleash it?) but now I'm looking it seems you just needed to do a full charged attack, maybe just needed some more feedback.
I was interested in using mouse movement to dodge but the execution was a bit lacking, I didn't really know if I was doing a dodge or not. But it was a good attempt at something a bit different and novel. :)
I hope you polish this up a bit more in a post jam build! Will keep an eye on it. :)